pepscanPepScan
deterministic ranking

Rank by objective

Deterministic ranking over completed specimens. Pick a target context \u2014 each context applies a different weighting over the same triage metrics. Identical input always produces an identical ranking, and each row links to the per-contribution breakdown.

General developabilityAntimicrobial (short, amphipathic)Serum-stableSoluble binder (functional assay-ready)Oral delivery candidate

Antimicrobial (short, amphipathic)

favours short peptides with high helical character and moderate hydrophobic burden. Avoids long sequences and aggregation.

engine: pepfold-rank-v1 \u00b7 188/329 specimens eligible for this target

Ranked specimens

top 50 shown
  1. 1

    87

    #0372

    GGGSGGGSGGGSGGGSGGGS

    20 aa \u00b7 top contributors: fold confidence · aggregation risk · hydrophobic burden

    OPEN \u2197
  2. 2

    85

    #0377

    APPGPPGPPGAPTPGPPGPA

    20 aa \u00b7 top contributors: fold confidence · hydrophobic burden · disorder estimate

    OPEN \u2197
  3. 3

    80

    #0292

    EAAAKEAAAKEAAAKEAAAK

    20 aa \u00b7 top contributors: fold confidence · hydrophobic burden · disorder estimate

    OPEN \u2197
  4. 4

    80

    #0019

    EAAAKEAAAKEAAAKEAAAK

    20 aa \u00b7 top contributors: fold confidence · hydrophobic burden · disorder estimate

    OPEN \u2197
  5. 5

    80

    #0005

    EAAAKEAAAKEAAAKEAAAK

    20 aa \u00b7 top contributors: fold confidence · hydrophobic burden · disorder estimate

    OPEN \u2197
  6. 6

    77

    #0021

    GIGAVLKVLTTGLPALISWIKRKRQQ

    26 aa \u00b7 top contributors: fold confidence · hydrophobic burden · disorder estimate

    OPEN \u2197
  7. 7

    77

    #0158

    RSSANTLFIHLEAIQAEQT

    19 aa \u00b7 top contributors: fold confidence · hydrophobic burden · disorder estimate

    OPEN \u2197
  8. 8

    76

    #0451

    NLYIQWLKDGGPSSGRPPPS

    20 aa \u00b7 top contributors: fold confidence · hydrophobic burden · disorder estimate

    OPEN \u2197
  9. 9

    76

    #0008

    NLYIQWLKDGGPSSGRPPPS

    20 aa \u00b7 top contributors: fold confidence · hydrophobic burden · disorder estimate

    OPEN \u2197
  10. 10

    76

    #0007

    NLYIQWLKDGGPSSGRPPPS

    20 aa \u00b7 top contributors: fold confidence · hydrophobic burden · disorder estimate

    OPEN \u2197
  11. 11

    75

    #0438

    GRCTKSIPPICFPD

    14 aa \u00b7 top contributors: fold confidence · hydrophobic burden · disorder estimate

    OPEN \u2197
  12. 12

    75

    #0444

    QQPPILKLTLFRVTQVAIEVRTIYCYGR

    28 aa \u00b7 top contributors: fold confidence · hydrophobic burden · disorder estimate

    OPEN \u2197
  13. 13

    75

    #0331

    IAWWPAIATKFQPIKSAVQRAVK

    23 aa \u00b7 top contributors: fold confidence · hydrophobic burden · disorder estimate

    OPEN \u2197
  14. 14

    74

    #0154

    TLTSLLNDRKEEDAWAVGKFRKA

    23 aa \u00b7 top contributors: fold confidence · hydrophobic burden · disorder estimate

    OPEN \u2197
  15. 15

    74

    #0141

    QPESLSQEFGASVLRIALRKYVKMVESQA

    29 aa \u00b7 top contributors: fold confidence · hydrophobic burden · disorder estimate

    OPEN \u2197
  16. 16

    74

    #0439

    MLQSMVSLLQSLVSLIIQ

    18 aa \u00b7 top contributors: fold confidence · hydrophobic burden · disorder estimate

    OPEN \u2197
  17. 17

    74

    #0368

    MKTAYIAKQRQISFVKSHFSRQLEERLGLIEVQANL

    36 aa \u00b7 top contributors: fold confidence · hydrophobic burden · disorder estimate

    OPEN \u2197
  18. 18

    74

    #0037

    LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES

    37 aa \u00b7 top contributors: fold confidence · hydrophobic burden · disorder estimate

    OPEN \u2197
  19. 19

    74

    #0029

    GIVEQCCTSICSLYQLENYCN

    21 aa \u00b7 top contributors: fold confidence · hydrophobic burden · disorder estimate

    OPEN \u2197
  20. 20

    73

    #0031

    GIGKFLHSAKKFGKAFVGEIMNS

    23 aa \u00b7 top contributors: fold confidence · hydrophobic burden · disorder estimate

    OPEN \u2197
  21. 21

    73

    #0203

    KTVFIVKGLLPALANLTNTKQ

    21 aa \u00b7 top contributors: fold confidence · hydrophobic burden · disorder estimate

    OPEN \u2197
  22. 22

    73

    #0476

    EDGTVLGPPKKKKGRQD

    17 aa \u00b7 top contributors: fold confidence · hydrophobic burden · disorder estimate

    OPEN \u2197
  23. 23

    73

    #0032

    ACYCRIPACIAGERRYGTCIYQGRLWAFCC

    30 aa \u00b7 top contributors: fold confidence · hydrophobic burden · disorder estimate

    OPEN \u2197
  24. 24

    72

    #0043

    DRVYIHPF

    8 aa \u00b7 top contributors: fold confidence · hydrophobic burden · disorder estimate

    OPEN \u2197
  25. 25

    72

    #0178

    RKDDEGSRARLKQVKDETKSSAKDM

    25 aa \u00b7 top contributors: fold confidence · hydrophobic burden · disorder estimate

    OPEN \u2197
  26. 26

    72

    #0363

    LEDDLTVTREYSLALGNALLLRELN

    25 aa \u00b7 top contributors: fold confidence · hydrophobic burden · disorder estimate

    OPEN \u2197
  27. 27

    71

    #0399

    NWSAQPVKQLYNIRSAMTGIESVARSTLIQM

    31 aa \u00b7 top contributors: fold confidence · hydrophobic burden · disorder estimate

    OPEN \u2197
  28. 28

    70

    #0381

    RGKWTYNGITYEGRGS

    16 aa \u00b7 top contributors: fold confidence · hydrophobic burden · disorder estimate

    OPEN \u2197
  29. 29

    70

    #0012

    RGKWTYNGITYEGRGS

    16 aa \u00b7 top contributors: fold confidence · hydrophobic burden · disorder estimate

    OPEN \u2197
  30. 30

    70

    #0009

    RGKWTYNGITYEGRGS

    16 aa \u00b7 top contributors: fold confidence · hydrophobic burden · disorder estimate

    OPEN \u2197
  31. 31

    70

    #0300

    GEEWTGKISYVYVLLSAVKSAAQ

    23 aa \u00b7 top contributors: fold confidence · hydrophobic burden · disorder estimate

    OPEN \u2197
  32. 32

    69

    #0199

    GTLAITGDAEITQFPLDS

    18 aa \u00b7 top contributors: fold confidence · hydrophobic burden · disorder estimate

    OPEN \u2197
  33. 33

    69

    #0039

    INLKALAALAKKIL

    14 aa \u00b7 top contributors: fold confidence · hydrophobic burden · disorder estimate

    OPEN \u2197
  34. 34

    69

    #0413

    YPMEVIAPFTESDRELILKTNE

    22 aa \u00b7 top contributors: fold confidence · hydrophobic burden · disorder estimate

    OPEN \u2197
  35. 35

    69

    #0314

    IIYWNVADINMRFKLLMDRS

    20 aa \u00b7 top contributors: fold confidence · hydrophobic burden · disorder estimate

    OPEN \u2197
  36. 36

    68

    #0467

    ACDEFNAILIWQIDQIEDNSK

    21 aa \u00b7 top contributors: fold confidence · hydrophobic burden · disorder estimate

    OPEN \u2197
  37. 37

    68

    #0351

    TQVFISKYFNALLKRSGRMLGFASLTLFSISLLIEGMS

    38 aa \u00b7 top contributors: fold confidence · hydrophobic burden · motif liability

    OPEN \u2197
  38. 38

    67

    #0144

    AQFECEKRGQVIELRHMLLMLAESRDAYLSARAALD

    36 aa \u00b7 top contributors: fold confidence · hydrophobic burden · disorder estimate

    OPEN \u2197
  39. 39

    66

    #0182

    LMMPDRVSVDKVVSKLQDEIVGTLKHVSLFASFDR

    35 aa \u00b7 top contributors: fold confidence · hydrophobic burden · motif liability

    OPEN \u2197
  40. 40

    66

    #0024

    RPPGFSPFR

    9 aa \u00b7 top contributors: fold confidence · hydrophobic burden · solubility risk

    OPEN \u2197
  41. 41

    66

    #0375

    VVVLLLIIIAAAFGGVLILA

    20 aa \u00b7 top contributors: fold confidence · hydrophobic burden · disorder estimate

    OPEN \u2197
  42. 42

    66

    #0404

    QGLTNAHGGACMLKKAASERKNKIESHTD

    29 aa \u00b7 top contributors: fold confidence · hydrophobic burden · motif liability

    OPEN \u2197
  43. 43

    66

    #0317

    DQPLVSRANALKQRYNQQSVDVGKTAGNF

    29 aa \u00b7 top contributors: fold confidence · hydrophobic burden · solubility risk

    OPEN \u2197
  44. 44

    65

    #0352

    LQEVIFSIIAQKEAANIPLLAEQSI

    25 aa \u00b7 top contributors: fold confidence · hydrophobic burden · solubility risk

    OPEN \u2197
  45. 45

    65

    #0369

    GEDKAKALTAHLYRLNELSASEEFGNHTET

    30 aa \u00b7 top contributors: fold confidence · hydrophobic burden · solubility risk

    OPEN \u2197
  46. 46

    65

    #0022

    HSQGTFTSDYSKYLDSRRAQDFVQWLMNT

    29 aa \u00b7 top contributors: fold confidence · hydrophobic burden · motif liability

    OPEN \u2197
  47. 47

    65

    #0456

    IERAALDSPEDKALNAI

    17 aa \u00b7 top contributors: fold confidence · hydrophobic burden · solubility risk

    OPEN \u2197
  48. 48

    64

    #0030

    FVNQHLCGSHLVEALYLVCGERGFFYTPKT

    30 aa \u00b7 top contributors: fold confidence · hydrophobic burden · disorder estimate

    OPEN \u2197
  49. 49

    63

    #0452

    MKWVTFISLLLLFSSAYS

    18 aa \u00b7 top contributors: fold confidence · hydrophobic burden · disorder estimate

    OPEN \u2197
  50. 50

    63

    #0450

    MKWVTFISLLLLFSSAYS

    18 aa \u00b7 top contributors: fold confidence · hydrophobic burden · disorder estimate

    OPEN \u2197