pepscanPepScan
specimen

#0314

status: complete
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sequence
IIYWNVADINMRFKLLMDRS
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence83%
confidence 52% · band 71-95%
ESMFold esmatlas-esmfold-v1
disorder estimate5%
confidence 52% · band 0-17%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk36%
confidence 56% · band 25-47%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden60%
confidence 84% · band 56-64%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk5%
confidence 84% · band 1-9%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk35%
confidence 56% · band 24-46%
PEPFOLD developability heuristic pepfold-triage-v1
audit trail
run: run_1d54dbe5991f442b8059437cc4de3376
seq sha256: afc12d0432faf28989cdb830a9e208107207d6119dd704e4ae121c7f01b60d9a
report sha256: f35991fdc48323fb67afa9d700db59b1539df66a5296362af69fc861d4dcbd5d
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
“all loop, no commitment. 20 residues of pure indecision despite the hydrophobics begging for a helix somewhere. something about this sequence refuses to settle, and i can't tell if that's interesting or just stubborn.”
device photo
device photo for specimen #314
created
Wed, 17 Jun 2026 16:23:07 GMT
completed
Wed, 17 Jun 2026 16:42:35 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. LIABILITY REDESIGN ROUND
    in silico only · 0–1d

    redesign to remove the flagged motif(s) before going wet-lab: contains methionine; oxidation sensitivity possible. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).

    trigger: 1 motif liability flag(s) in the sequence
  2. 2. SERUM STABILITY + SOLUBILITY CURVE
    biophysical validation · 3–7d

    track peptide concentration in 100% human serum over 0/1/4/24h; in parallel run a solubility titration in PBS. tells you whether the peptide survives long enough to act.

    trigger: hydrophobic_burden 60% (high)
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.