specimen

#0413

status: complete
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sequence
YPMEVIAPFTESDRELILKTNE
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence75%
confidence 52% · band 63-87%
ESMFold esmatlas-esmfold-v1
disorder estimate5%
confidence 52% · band 0-17%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk26%
confidence 56% · band 15-37%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden41%
confidence 84% · band 37-45%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk14%
confidence 84% · band 10-18%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk27%
confidence 56% · band 16-38%
PEPFOLD developability heuristic pepfold-triage-v1
audit trail
run: run_fbac970b7193435ba9200b18c8e2fc15
seq sha256: 38bf3c06260aa81bd65ed38ff0ea071b90e9f9f7a80a6317030123439ff28208
report sha256: a4c55ca3fcf9be3e70113aec306c9cf3f2977597037de0cfaf3d79fffa80e35b
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
all loop, no commitment. 22 residues that refuse to pick a structure, just drifting through conformational space. the sequence looks reasonable on paper but the fold says otherwise.
device photo
device photo for specimen #413
created
Thu, 18 Jun 2026 04:23:29 GMT
completed
Thu, 18 Jun 2026 04:36:23 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. LIABILITY REDESIGN ROUND
    in silico only · 0–1d

    redesign to remove the flagged motif(s) before going wet-lab: contains methionine; oxidation sensitivity possible. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).

    trigger: 1 motif liability flag(s) in the sequence
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.