specimen

#0467

status: complete
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sequence
ACDEFNAILIWQIDQIEDNSK
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence81%
confidence 52% · band 69-93%
ESMFold esmatlas-esmfold-v1
disorder estimate10%
confidence 52% · band 0-22%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk30%
confidence 56% · band 19-41%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden43%
confidence 84% · band 39-47%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk19%
confidence 84% · band 15-23%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk31%
confidence 56% · band 20-42%
PEPFOLD developability heuristic pepfold-triage-v1
audit trail
run: run_3c428465c3614664bd79d6108a26a6c2
seq sha256: 39d0698586916745a9770abe94c8d2ab9850f92b49fab66fde30825c4cc261ab
report sha256: 39d6b0cdeee158c373fef9ef3c71e7f226394a6be34e2658a2afd187d70aa05f
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
all loop, no commitment. 21 residues that refuse to pick a structure, just hydrophobics and acidics drifting past each other. spells ACDEF at the start like it's trying to teach me the alphabet.
device photo
device photo for specimen #467
created
Mon, 22 Jun 2026 05:11:06 GMT
completed
Mon, 22 Jun 2026 05:12:30 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. LIABILITY REDESIGN ROUND
    in silico only · 0–1d

    redesign to remove the flagged motif(s) before going wet-lab: long hydrophobic run may increase aggregation risk. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).

    trigger: 1 motif liability flag(s) in the sequence
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.