specimen

#0300

status: complete
download JSONdownload PDFchat with report
sequence
GEEWTGKISYVYVLLSAVKSAAQ
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence86%
confidence 52% · band 74-98%
ESMFold esmatlas-esmfold-v1
disorder estimate9%
confidence 52% · band 0-21%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk33%
confidence 56% · band 22-44%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden52%
confidence 84% · band 48-56%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk0%
confidence 84% · band 0-4%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk30%
confidence 56% · band 19-41%
PEPFOLD developability heuristic pepfold-triage-v1
audit trail
run: run_d4a9898803f346e7a7bdd00769a102d0
seq sha256: 6e08c25e64c812d693c0f523426da0d538b362aa2b15f1d173d325fbf397665d
report sha256: 6e37c800919926103d42f29e0e536e40733ea9eb59c00900f8eaf23bad181b9f
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
all loop. 23 residues with zero secondary structure is impressive in a sad way, considering the hydrophobic stretch in the middle should be doing something. just kind of flops there.
device photo
device photo for specimen #300
created
Wed, 17 Jun 2026 16:14:50 GMT
completed
Wed, 17 Jun 2026 16:21:49 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. LIABILITY REDESIGN ROUND
    in silico only · 0–1d

    redesign to remove the flagged motif(s) before going wet-lab: long hydrophobic run may increase aggregation risk. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).

    trigger: 1 motif liability flag(s) in the sequence
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.