specimen

#0404

status: complete
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sequence
QGLTNAHGGACMLKKAASERKNKIESHTD
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence75%
confidence 52% · band 63-87%
ESMFold esmatlas-esmfold-v1
disorder estimate31%
confidence 52% · band 19-43%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk19%
confidence 56% · band 8-30%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden28%
confidence 84% · band 24-32%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk7%
confidence 84% · band 3-11%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk18%
confidence 56% · band 7-29%
PEPFOLD developability heuristic pepfold-triage-v1
audit trail
run: run_f4063775cd7148e79e1c29d78f4b4fc9
seq sha256: 27499edd181ba64591e874f3b0bb6f34d87d9dfa1f2e819d04b2c6e1c332de3a
report sha256: f7e6a8910533dfff67935e00836724c35abe4fd3e9bb08d7edbc862cb6ce4630
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
all loop, no structure. 29 residues of pure floppiness, nothing committing to anything. lots of charge scattered through it, lysines and glutamates jostling. reads like a disordered tail that lost its protein.
device photo
device photo for specimen #404
created
Thu, 18 Jun 2026 04:18:19 GMT
completed
Thu, 18 Jun 2026 04:22:22 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. LIABILITY REDESIGN ROUND
    in silico only · 0–1d

    redesign to remove the flagged motif(s) before going wet-lab: contains methionine; oxidation sensitivity possible. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).

    trigger: 1 motif liability flag(s) in the sequence
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.