pepscanPepScan
deterministic ranking

Rank by objective

Deterministic ranking over completed specimens. Pick a target context \u2014 each context applies a different weighting over the same triage metrics. Identical input always produces an identical ranking, and each row links to the per-contribution breakdown.

General developabilityAntimicrobial (short, amphipathic)Serum-stableSoluble binder (functional assay-ready)Oral delivery candidate

Oral delivery candidate

small, low-disorder, low-hydrophobic-burden. Penalises any motif liability, oral routes are unforgiving.

engine: pepfold-rank-v1 \u00b7 54/329 specimens eligible for this target

Ranked specimens

top 50 shown
  1. 1

    100

    #0372

    GGGSGGGSGGGSGGGSGGGS

    20 aa \u00b7 top contributors: fold confidence · aggregation risk · hydrophobic burden

    OPEN \u2197
  2. 2

    93

    #0377

    APPGPPGPPGAPTPGPPGPA

    20 aa \u00b7 top contributors: fold confidence · disorder estimate · solubility risk

    OPEN \u2197
  3. 3

    78

    #0158

    RSSANTLFIHLEAIQAEQT

    19 aa \u00b7 top contributors: fold confidence · disorder estimate · solubility risk

    OPEN \u2197
  4. 4

    75

    #0292

    EAAAKEAAAKEAAAKEAAAK

    20 aa \u00b7 top contributors: fold confidence · disorder estimate · solubility risk

    OPEN \u2197
  5. 5

    75

    #0019

    EAAAKEAAAKEAAAKEAAAK

    20 aa \u00b7 top contributors: fold confidence · disorder estimate · solubility risk

    OPEN \u2197
  6. 6

    75

    #0005

    EAAAKEAAAKEAAAKEAAAK

    20 aa \u00b7 top contributors: fold confidence · disorder estimate · solubility risk

    OPEN \u2197
  7. 7

    73

    #0024

    RPPGFSPFR

    9 aa \u00b7 top contributors: fold confidence · solubility risk · aggregation risk

    OPEN \u2197
  8. 8

    73

    #0043

    DRVYIHPF

    8 aa \u00b7 top contributors: fold confidence · disorder estimate · solubility risk

    OPEN \u2197
  9. 9

    71

    #0199

    GTLAITGDAEITQFPLDS

    18 aa \u00b7 top contributors: fold confidence · solubility risk · aggregation risk

    OPEN \u2197
  10. 10

    69

    #0476

    EDGTVLGPPKKKKGRQD

    17 aa \u00b7 top contributors: fold confidence · disorder estimate · solubility risk

    OPEN \u2197
  11. 11

    68

    #0438

    GRCTKSIPPICFPD

    14 aa \u00b7 top contributors: fold confidence · disorder estimate · solubility risk

    OPEN \u2197
  12. 12

    67

    #0451

    NLYIQWLKDGGPSSGRPPPS

    20 aa \u00b7 top contributors: fold confidence · disorder estimate · solubility risk

    OPEN \u2197
  13. 13

    67

    #0008

    NLYIQWLKDGGPSSGRPPPS

    20 aa \u00b7 top contributors: fold confidence · disorder estimate · solubility risk

    OPEN \u2197
  14. 14

    67

    #0007

    NLYIQWLKDGGPSSGRPPPS

    20 aa \u00b7 top contributors: fold confidence · disorder estimate · solubility risk

    OPEN \u2197
  15. 15

    65

    #0427

    RVQLHALESSPAKRRKQ

    17 aa \u00b7 top contributors: fold confidence · solubility risk · aggregation risk

    OPEN \u2197
  16. 16

    64

    #0040

    YGGFLRRIRPKLKWDNQ

    17 aa \u00b7 top contributors: fold confidence · solubility risk · aggregation risk

    OPEN \u2197
  17. 17

    63

    #0456

    IERAALDSPEDKALNAI

    17 aa \u00b7 top contributors: fold confidence · solubility risk · aggregation risk

    OPEN \u2197
  18. 18

    61

    #0381

    RGKWTYNGITYEGRGS

    16 aa \u00b7 top contributors: fold confidence · solubility risk · disorder estimate

    OPEN \u2197
  19. 19

    61

    #0012

    RGKWTYNGITYEGRGS

    16 aa \u00b7 top contributors: fold confidence · solubility risk · disorder estimate

    OPEN \u2197
  20. 20

    61

    #0009

    RGKWTYNGITYEGRGS

    16 aa \u00b7 top contributors: fold confidence · solubility risk · disorder estimate

    OPEN \u2197
  21. 21

    58

    #0437

    SLIPPY

    6 aa \u00b7 top contributors: fold confidence · solubility risk · aggregation risk

    OPEN \u2197
  22. 22

    57

    #0408

    NVQDNPVLLIRYSHQF

    16 aa \u00b7 top contributors: fold confidence · solubility risk · aggregation risk

    OPEN \u2197
  23. 23

    55

    #0470

    VGKDPLARYIIIRLYNL

    17 aa \u00b7 top contributors: fold confidence · solubility risk · aggregation risk

    OPEN \u2197
  24. 24

    54

    #0439

    MLQSMVSLLQSLVSLIIQ

    18 aa \u00b7 top contributors: fold confidence · disorder estimate · solubility risk

    OPEN \u2197
  25. 25

    53

    #0354

    DDRAKDNVLLSSPTKG

    16 aa \u00b7 top contributors: fold confidence · solubility risk · aggregation risk

    OPEN \u2197
  26. 26

    53

    #0468

    ACESEIL

    7 aa \u00b7 top contributors: fold confidence · solubility risk · aggregation risk

    OPEN \u2197
  27. 27

    52

    #0038

    CNCKAPETALCARRCQQH

    18 aa \u00b7 top contributors: fold confidence · solubility risk · aggregation risk

    OPEN \u2197
  28. 28

    51

    #0044

    EHWSYGLRPG

    10 aa \u00b7 top contributors: fold confidence · solubility risk · aggregation risk

    OPEN \u2197
  29. 29

    51

    #0140

    FIRYGSNEIPGEAIHCASA

    19 aa \u00b7 top contributors: fold confidence · solubility risk · aggregation risk

    OPEN \u2197
  30. 30

    50

    #0314

    IIYWNVADINMRFKLLMDRS

    20 aa \u00b7 top contributors: fold confidence · disorder estimate · solubility risk

    OPEN \u2197
  31. 31

    49

    #0323

    RKKLKLKGRLASRQLE

    16 aa \u00b7 top contributors: fold confidence · solubility risk · aggregation risk

    OPEN \u2197
  32. 32

    46

    #0039

    INLKALAALAKKIL

    14 aa \u00b7 top contributors: fold confidence · disorder estimate · motif liability

    OPEN \u2197
  33. 33

    46

    #0366

    ACDEFGHIKLMNPQRSTVWY

    20 aa \u00b7 top contributors: fold confidence · solubility risk · motif liability

    OPEN \u2197
  34. 34

    46

    #0016

    ACDEFGHIKLMNPQRSTVWY

    20 aa \u00b7 top contributors: fold confidence · solubility risk · motif liability

    OPEN \u2197
  35. 35

    46

    #0015

    ACDEFGHIKLMNPQRSTVWY

    20 aa \u00b7 top contributors: fold confidence · solubility risk · motif liability

    OPEN \u2197
  36. 36

    46

    #0214

    AVSSRRGTNEMFGSIRLMIR

    20 aa \u00b7 top contributors: fold confidence · solubility risk · motif liability

    OPEN \u2197
  37. 37

    44

    #0023

    RPKPQQFFGLM

    11 aa \u00b7 top contributors: fold confidence · solubility risk · motif liability

    OPEN \u2197
  38. 38

    43

    #0025

    CYIQNCPLG

    9 aa \u00b7 top contributors: fold confidence · solubility risk · aggregation risk

    OPEN \u2197
  39. 39

    43

    #0371

    GAVLIAGGTSNQDEKRHFPY

    20 aa \u00b7 top contributors: fold confidence · solubility risk · motif liability

    OPEN \u2197
  40. 40

    42

    #0478

    KTSALTSDFNMQLGPPLEC

    19 aa \u00b7 top contributors: fold confidence · solubility risk · aggregation risk

    OPEN \u2197
  41. 41

    38

    #0375

    VVVLLLIIIAAAFGGVLILA

    20 aa \u00b7 top contributors: fold confidence · disorder estimate · motif liability

    OPEN \u2197
  42. 42

    38

    #0254

    SSENRWRGYRGDGKTTINL

    19 aa \u00b7 top contributors: fold confidence · solubility risk · hydrophobic burden

    OPEN \u2197
  43. 43

    36

    #0026

    CYFQNCPRG

    9 aa \u00b7 top contributors: fold confidence · solubility risk · hydrophobic burden

    OPEN \u2197
  44. 44

    35

    #0042

    YGGFL

    5 aa \u00b7 top contributors: fold confidence · solubility risk · aggregation risk

    OPEN \u2197
  45. 45

    34

    #0253

    VNTCEALDISLEQGPLAMSI

    20 aa \u00b7 top contributors: fold confidence · solubility risk · motif liability

    OPEN \u2197
  46. 46

    33

    #0155

    TPGLPDSVMILRATEDIPG

    19 aa \u00b7 top contributors: fold confidence · solubility risk · motif liability

    OPEN \u2197
  47. 47

    32

    #0148

    ENMDLWPEIVIHNCCL

    16 aa \u00b7 top contributors: fold confidence · disorder estimate · solubility risk

    OPEN \u2197
  48. 48

    28

    #0452

    MKWVTFISLLLLFSSAYS

    18 aa \u00b7 top contributors: fold confidence · disorder estimate · solubility risk

    OPEN \u2197
  49. 49

    28

    #0450

    MKWVTFISLLLLFSSAYS

    18 aa \u00b7 top contributors: fold confidence · disorder estimate · solubility risk

    OPEN \u2197
  50. 50

    28

    #0020

    MKWVTFISLLLLFSSAYS

    18 aa \u00b7 top contributors: fold confidence · disorder estimate · solubility risk

    OPEN \u2197