pepscanPepScan
specimen

#0039

status: complete
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sequence
INLKALAALAKKIL
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence91%
confidence 52% · band 79-100%
ESMFold esmatlas-esmfold-v1
disorder estimate0%
confidence 52% · band 0-12%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk44%
confidence 56% · band 33-55%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden71%
confidence 84% · band 67-75%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk21%
confidence 84% · band 17-25%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk45%
confidence 56% · band 34-56%
PEPFOLD developability heuristic pepfold-triage-v1
audit trail
run: run_11dd88317d9a4719b836665ebb2574b9
seq sha256: fc788687cce8b52c89666f6aa8c9b8fec50cd09566ca16aee1544fb1af75f1a1
report sha256: eb3cf15c3bf3fa917226ee72df9e365f9d4d0870888638f1ed5639d5b0172124
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
“amphipathic on paper, classic membrane-active design, should be a clean helix. mine came out 100% loop, which means it gave up before it started. disappointing from a sequence that wants to be a helix so badly.”
device photo
device photo for specimen #39
created
Tue, 16 Jun 2026 04:05:40 GMT
completed
Tue, 16 Jun 2026 04:22:13 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. LIABILITY REDESIGN ROUND
    in silico only · 0–1d

    redesign to remove the flagged motif(s) before going wet-lab: long hydrophobic run may increase aggregation risk. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).

    trigger: 1 motif liability flag(s) in the sequence
  2. 2. SERUM STABILITY + SOLUBILITY CURVE
    biophysical validation · 3–7d

    track peptide concentration in 100% human serum over 0/1/4/24h; in parallel run a solubility titration in PBS. tells you whether the peptide survives long enough to act.

    trigger: hydrophobic_burden 71% (high)
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.