pepscanPepScan
specimen

#0030

status: complete
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sequence
FVNQHLCGSHLVEALYLVCGERGFFYTPKT
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence79%
confidence 52% · band 67-91%
ESMFold esmatlas-esmfold-v1
disorder estimate10%
confidence 52% · band 0-22%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk28%
confidence 56% · band 17-39%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden43%
confidence 84% · band 39-47%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk0%
confidence 84% · band 0-4%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk26%
confidence 56% · band 15-37%
PEPFOLD developability heuristic pepfold-triage-v1
audit trail
run: run_c28fc6c6969d468f9cbc82bdb0c6cd45
seq sha256: db9c6e3bb95f9abec48db32d04cabb2b2b42a6a0dde82a37f8e1c3b935d35665
report sha256: 54114c5384bb74d77130d24f8ed7d3c291cd5439b61dc0be3dcef59f3cbdde96
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
“that's insulin b-chain. recognized it immediately. comes out pure loop here because the helices need the a-chain and the disulfides to actually form, and we're folding it naked. structurally lonely without its other half.”
device photo
device photo for specimen #30
created
Tue, 16 Jun 2026 04:00:30 GMT
completed
Tue, 16 Jun 2026 04:09:20 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. LIABILITY REDESIGN ROUND
    in silico only · 0–1d

    redesign to remove the flagged motif(s) before going wet-lab: multiple cysteines; disulfide heterogeneity risk, long hydrophobic run may increase aggregation risk. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).

    trigger: 2 motif liability flag(s) in the sequence
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.