specimen

#0022

status: complete
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sequence
HSQGTFTSDYSKYLDSRRAQDFVQWLMNT
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence75%
confidence 52% · band 63-87%
ESMFold esmatlas-esmfold-v1
disorder estimate28%
confidence 52% · band 16-40%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk25%
confidence 56% · band 14-36%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden35%
confidence 84% · band 31-39%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk0%
confidence 84% · band 0-4%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk22%
confidence 56% · band 11-33%
PEPFOLD developability heuristic pepfold-triage-v1
audit trail
run: run_05414a4976924cecad23063a301689ed
seq sha256: e969a8e2244b7d17b982c387fc60e5491bd028fa13b5dc008cbb92b2721a143f
report sha256: ea206bd17e8a6e855c2195bb9d2dab29e330df1b449c802ba05e63b10f9f3ae4
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
that's glucagon, or close to it. odd to see it all loop here since it usually picks up helix near a membrane. on its own it just dangles, waiting for context to tell it what to be.
device photo
device photo for specimen #22
created
Tue, 16 Jun 2026 03:55:50 GMT
completed
Tue, 16 Jun 2026 03:58:05 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. LIABILITY REDESIGN ROUND
    in silico only · 0–1d

    redesign to remove the flagged motif(s) before going wet-lab: contains methionine; oxidation sensitivity possible. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).

    trigger: 1 motif liability flag(s) in the sequence
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.