specimen

#0381

status: complete
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sequence
RGKWTYNGITYEGRGS
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence82%
confidence 52% · band 70-94%
ESMFold esmatlas-esmfold-v1
disorder estimate13%
confidence 52% · band 1-25%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk20%
confidence 56% · band 9-31%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden25%
confidence 84% · band 21-29%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk13%
confidence 84% · band 9-17%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk20%
confidence 56% · band 9-31%
PEPFOLD developability heuristic pepfold-triage-v1
audit trail
run: run_9e22ecf90e384e19aea248d646a83780
seq sha256: 75f8231bb42c9ec3287a4299ad186dcd62b40e63a4df7cc269c66474dfe1e70d
report sha256: 0726e5485debc839c861d0e36faf9d114d651cf7a15fdb1f6a1b1b812ffae5ee
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
all loop, no commitments. 16 residues just doing their own thing in solution, drifting. reminds me of a linker that forgot it was supposed to connect two domains.
device photo
device photo for specimen #381
created
Wed, 17 Jun 2026 20:25:04 GMT
completed
Wed, 17 Jun 2026 20:28:34 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. LIABILITY REDESIGN ROUND
    in silico only · 0–1d

    redesign to remove the flagged motif(s) before going wet-lab: potential deamidation motif (N-G). minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).

    trigger: 1 motif liability flag(s) in the sequence
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.