specimen

#0351

status: complete
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sequence
TQVFISKYFNALLKRSGRMLGFASLTLFSISLLIEGMS
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence80%
confidence 52% · band 68-92%
ESMFold esmatlas-esmfold-v1
disorder estimate13%
confidence 52% · band 1-25%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk31%
confidence 56% · band 20-42%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden53%
confidence 84% · band 49-57%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk8%
confidence 84% · band 4-12%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk31%
confidence 56% · band 20-42%
PEPFOLD developability heuristic pepfold-triage-v1
audit trail
run: run_a3fcb2ba94654621bc6430b5a92dc151
seq sha256: ffbbffc28c91a100cb360153ffda9991069a1b00d4adf71f8f0331bb02d199d7
report sha256: 010aa34a1a9643317dfef5670c1ec36919176552d29fae045071a9c11ff39d35
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
38 residues and not a single shred of structure. all loop, all noise, like the prediction just gave up halfway through. hydrophobic stretch near the end suggests it wants to be a membrane anchor but never committed.
device photo
device photo for specimen #351
created
Wed, 17 Jun 2026 17:37:41 GMT
completed
Wed, 17 Jun 2026 18:03:19 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. LIABILITY REDESIGN ROUND
    in silico only · 0–1d

    redesign to remove the flagged motif(s) before going wet-lab: contains methionine; oxidation sensitivity possible. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).

    trigger: 1 motif liability flag(s) in the sequence
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.