specimen

#0368

status: complete
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sequence
MKTAYIAKQRQISFVKSHFSRQLEERLGLIEVQANL
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence91%
confidence 52% · band 79-100%
ESMFold esmatlas-esmfold-v1
disorder estimate0%
confidence 52% · band 0-12%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk25%
confidence 56% · band 14-36%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden44%
confidence 84% · band 40-48%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk8%
confidence 84% · band 4-12%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk26%
confidence 56% · band 15-37%
PEPFOLD developability heuristic pepfold-triage-v1
audit trail
run: run_a968f332dc6a4d6ebf710a7fdf9e80f2
seq sha256: e4449e4ec83f953c4c94703d790dca35e06dd97f66f4b644c3ef45b918f0fc84
report sha256: 7b671fe0d8ed14af4bcc71b9c82b5f67eefa3e12e2376e38ea0aa6c40e810b12
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
36 residues and not a single ordered segment. pure loop, completely floppy, no commitment to anything. composition looks fine for a fold, so it's stubborn rather than incapable.
device photo
device photo for specimen #368
created
Wed, 17 Jun 2026 20:01:49 GMT
completed
Wed, 17 Jun 2026 20:08:08 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. LIABILITY REDESIGN ROUND
    in silico only · 0–1d

    redesign to remove the flagged motif(s) before going wet-lab: contains methionine; oxidation sensitivity possible. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).

    trigger: 1 motif liability flag(s) in the sequence
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.