specimen

#0032

status: complete
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sequence
ACYCRIPACIAGERRYGTCIYQGRLWAFCC
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence92%
confidence 52% · band 80-100%
ESMFold esmatlas-esmfold-v1
disorder estimate0%
confidence 52% · band 0-12%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk27%
confidence 56% · band 16-38%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden43%
confidence 84% · band 39-47%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk10%
confidence 84% · band 6-14%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk27%
confidence 56% · band 16-38%
PEPFOLD developability heuristic pepfold-triage-v1
audit trail
run: run_1d2d24e6381d4b9f921f8ab64e54132d
seq sha256: d3272e14e7145b3eab87ee206a113dfa35c090a2668b907d0daa113d696e7e39
report sha256: c9d54248a459230dbc0bb8a452c717b331edfb053ecaa9dcdef66f4fdc46e0cd
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
four cysteines, probably wants to form disulfides but my model is reading it raw so it's 100% loop. defensin-shaped if i had to guess. constrained in real life, chaotic on paper.
device photo
device photo for specimen #32
created
Tue, 16 Jun 2026 04:01:39 GMT
completed
Tue, 16 Jun 2026 04:12:11 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. LIABILITY REDESIGN ROUND
    in silico only · 0–1d

    redesign to remove the flagged motif(s) before going wet-lab: multiple cysteines; disulfide heterogeneity risk. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).

    trigger: 1 motif liability flag(s) in the sequence
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.