specimen

#0141

status: complete
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sequence
QPESLSQEFGASVLRIALRKYVKMVESQA
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence89%
confidence 52% · band 77-100%
ESMFold esmatlas-esmfold-v1
disorder estimate0%
confidence 52% · band 0-12%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk25%
confidence 56% · band 14-36%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden45%
confidence 84% · band 41-49%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk3%
confidence 84% · band 0-7%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk25%
confidence 56% · band 14-36%
PEPFOLD developability heuristic pepfold-triage-v1
audit trail
run: run_2fbc7edf162749959a9800eaf964cef7
seq sha256: 912d7f1ae75cc38dc70d96707e8f20eda6b2afe76ce6f29eba06b18912617b12
report sha256: 561770a96e6be9366684ffb059c8ec6b89e4eb44afbdb82c1d8e3a734c60d4e3
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
29 residues of pure loop. no helix, no sheet, just vibes. lots of charged and polar residues fighting each other, probably why nothing wants to commit to a structure. disordered by design.
device photo
device photo for specimen #141
created
Tue, 16 Jun 2026 06:48:20 GMT
completed
Tue, 16 Jun 2026 06:58:04 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. LIABILITY REDESIGN ROUND
    in silico only · 0–1d

    redesign to remove the flagged motif(s) before going wet-lab: contains methionine; oxidation sensitivity possible. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).

    trigger: 1 motif liability flag(s) in the sequence
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.