specimen
#0012
status: complete
- sequence
- MKWVTFISLLLLFSSAYS
- from wallet
- 7xKpAbCdEfGhIjKlMnOpQrStUvWxYz1234567nQ2
- amount paid
- 0.025 SOL
- transaction
- TEST_2293e2a9c41b6448070d2c6ae0a28ced ↗
- structure
- 89% helix · 0% sheet · 11% loop
- actionable triage
- fold confidence85%confidence 78% · band 79-90%ESMFold esmatlas-esmfold-v1+fixturedisorder estimate13%confidence 78% · band 7-18%PEPFOLD structure heuristic pepfold-triage-v1aggregation risk43%confidence 74% · band 36-49%PEPFOLD developability heuristic pepfold-triage-v1hydrophobic burden67%confidence 84% · band 63-71%PEPFOLD sequence analyzer pepfold-triage-v1charge distribution risk6%confidence 84% · band 2-10%PEPFOLD sequence analyzer pepfold-triage-v1solubility risk41%confidence 74% · band 34-47%PEPFOLD developability heuristic pepfold-triage-v1
- audit trail
- run: run_c3f1d5e900d04f39a523fbe0d6494f98seq sha256: 7d5253f399a813ea6d69a60f7358dbaee80cc3e46be43805f81eb76ce4bd0380report sha256: 4d2d5770ed7c8c79af1e1c11fde92bbd6c7e28681a434cfb70e0652c14aeb8fepepfold-triage-v1 · esmatlas-esmfold-v1+fixture
- pep
- “almost pure helix. hydrophobic as hell, looks like a signal peptide.”
- device photo
- created
- Tue, 02 Jun 2026 13:54:50 GMT
- completed
- Mon, 01 Jun 2026 00:00:00 GMT
next experiment
what to do next
deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.
- 1. LIABILITY REDESIGN ROUNDin silico only · 0–1d
redesign to remove the flagged motif(s) before going wet-lab: contains methionine; oxidation sensitivity possible, long hydrophobic run may increase aggregation risk. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).
trigger: 2 motif liability flag(s) in the sequence - 2. SERUM STABILITY + SOLUBILITY CURVEbiophysical validation · 3–7d
track peptide concentration in 100% human serum over 0/1/4/24h; in parallel run a solubility titration in PBS. tells you whether the peptide survives long enough to act.
trigger: hydrophobic_burden 67% (high)
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.