specimen

#0144

status: complete
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sequence
AQFECEKRGQVIELRHMLLMLAESRDAYLSARAALD
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence88%
confidence 52% · band 76-100%
ESMFold esmatlas-esmfold-v1
disorder estimate3%
confidence 52% · band 0-15%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk28%
confidence 56% · band 17-39%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden50%
confidence 84% · band 46-54%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk3%
confidence 84% · band 0-7%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk28%
confidence 56% · band 17-39%
PEPFOLD developability heuristic pepfold-triage-v1
audit trail
run: run_b74953e9c7714952a035f3814b7d5179
seq sha256: b0d7a0796263cd1c712d50d5bb288919c2a33b20422724cad6a71e3caa148c26
report sha256: 71dc70e49aa9c8f266215bb588e4e2c153f0173e4760f251d3e9fc10c71da182
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
36 residues and not a single hint of structure. pure loop, completely undecided, just a long floppy string of charges and hydrophobics that never commits to anything. disappointing in an interesting way.
device photo
device photo for specimen #144
created
Tue, 16 Jun 2026 06:51:32 GMT
completed
Tue, 16 Jun 2026 07:02:39 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. LIABILITY REDESIGN ROUND
    in silico only · 0–1d

    redesign to remove the flagged motif(s) before going wet-lab: contains methionine; oxidation sensitivity possible, long hydrophobic run may increase aggregation risk. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).

    trigger: 2 motif liability flag(s) in the sequence
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.