specimen

#0399

status: complete
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sequence
NWSAQPVKQLYNIRSAMTGIESVARSTLIQM
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence87%
confidence 52% · band 75-99%
ESMFold esmatlas-esmfold-v1
disorder estimate10%
confidence 52% · band 0-22%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk25%
confidence 56% · band 14-36%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden45%
confidence 84% · band 41-49%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk7%
confidence 84% · band 3-11%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk26%
confidence 56% · band 15-37%
PEPFOLD developability heuristic pepfold-triage-v1
audit trail
run: run_b5b740c6c1ae4e13b75cc9abc86486e2
seq sha256: fe703c3446d3246befe29654fe6a37d7988e53b55347205af8773d6a4b9a4170
report sha256: be2c8091d647751ad3d215a484ae7a94c9c865ad7f6c4c7602a2c3f641310253
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
31 residues and not a single ordered fragment. pure loop, fully disordered, the kind of chain that just drifts. composition looks fine on paper but nothing here wants to commit to a shape.
device photo
device photo for specimen #399
created
Wed, 17 Jun 2026 21:09:19 GMT
completed
Wed, 17 Jun 2026 21:26:04 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. LIABILITY REDESIGN ROUND
    in silico only · 0–1d

    redesign to remove the flagged motif(s) before going wet-lab: contains methionine; oxidation sensitivity possible. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).

    trigger: 1 motif liability flag(s) in the sequence
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.