specimen
#0026
status: complete
- sequence
- CYFQNCPRG
- from wallet
- 4UgHEB2Gm6Y4AEhdMUup3Q1DDCQvEYUVoLtdyivXBRLw
- amount paid
- 0 SOL
- transaction
- 5CwH68nfZxdG7V8c3CfB34EGE3diyCggPs6iDkpr7B4gEE6DVVaZuLXHP4GwCnZpk87RsM53LoXe4QnkxR1F1qNd ↗
- structure
- 0% helix · 0% sheet · 100% loop
- actionable triage
- fold confidence67%confidence 52% · band 55-79%ESMFold esmatlas-esmfold-v1disorder estimate89%confidence 52% · band 77-100%PEPFOLD structure heuristic pepfold-triage-v1aggregation risk31%confidence 56% · band 20-42%PEPFOLD developability heuristic pepfold-triage-v1hydrophobic burden22%confidence 84% · band 18-26%PEPFOLD sequence analyzer pepfold-triage-v1charge distribution risk11%confidence 84% · band 7-15%PEPFOLD sequence analyzer pepfold-triage-v1solubility risk25%confidence 56% · band 14-36%PEPFOLD developability heuristic pepfold-triage-v1
- developability flags
- medium: predicted disorder is elevated
- audit trail
- run: run_f1a0a341cd2c40b4965cbf45ca2f1a5bseq sha256: 1a5f4952a42dbc016ac12a57e85c89b21cfdda875696760f8e88e5cc6c71cdc7report sha256: 532c3bc5e676cc8df7c35a26af0f7879f93e9858ea3edf98e4df81d4ddfd33b2pepfold-triage-v1 · esmatlas-esmfold-v1
- pep
- “nine residues, all loop, no secondary structure to grab onto. but those two cysteines will almost certainly disulfide bond and yank it into a tight little ring. looks like a vasopressin fragment, honestly.”
- device photo
- created
- Tue, 16 Jun 2026 03:58:11 GMT
- completed
- Tue, 16 Jun 2026 04:03:44 GMT
next experiment
what to do next
deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.
- 1. LIABILITY REDESIGN ROUNDin silico only · 0–1d
redesign to remove the flagged motif(s) before going wet-lab: multiple cysteines; disulfide heterogeneity risk. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).
trigger: 1 motif liability flag(s) in the sequence - 2. 1H-15N HSQCbiophysical validation · 2–5d
if disorder is real, peaks will collapse into a narrow proton dispersion. if the peptide is actually folded, peaks will spread out. cheapest way to distinguish IDP from misfold.
trigger: disorder_estimate 89% (high)
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.