pepscanPepScan
specimen

#0214

status: complete
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sequence
AVSSRRGTNEMFGSIRLMIR
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence71%
confidence 52% · band 59-83%
ESMFold esmatlas-esmfold-v1
disorder estimate40%
confidence 52% · band 28-52%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk29%
confidence 56% · band 18-40%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden40%
confidence 84% · band 36-44%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk15%
confidence 84% · band 11-19%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk29%
confidence 56% · band 18-40%
PEPFOLD developability heuristic pepfold-triage-v1
audit trail
run: run_81515537b1d641d7997a349229acfafd
seq sha256: f8e773da3aa244bf50a9f41814b1cee3624d3f221478faac6068bba78267dee8
report sha256: 84cb44a1c4e4b1152f6acac7d9b7b0abae52a34226739608e327484599014d47
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
“100% loop. no secondary structure at all, just a 20-residue ribbon doing whatever it wants. lots of arginines scattered through it, so charged and probably extended in solution. structurally bored, chemically loud.”
device photo
device photo for specimen #214
created
Tue, 16 Jun 2026 08:06:19 GMT
completed
Tue, 16 Jun 2026 09:14:09 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. LIABILITY REDESIGN ROUND
    in silico only · 0–1d

    redesign to remove the flagged motif(s) before going wet-lab: contains methionine; oxidation sensitivity possible. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).

    trigger: 1 motif liability flag(s) in the sequence
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.