specimen

#0468

status: complete
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sequence
ACESEIL
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence68%
confidence 52% · band 56-80%
ESMFold esmatlas-esmfold-v1
disorder estimate71%
confidence 52% · band 59-83%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk37%
confidence 56% · band 26-48%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden43%
confidence 84% · band 39-47%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk29%
confidence 84% · band 25-33%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk37%
confidence 56% · band 26-48%
PEPFOLD developability heuristic pepfold-triage-v1
developability flags
medium: predicted disorder is elevated
synthesis hints
  • - high absolute charge density; validate purification conditions
audit trail
run: run_080c97a676d54cf39bb302baf079da51
seq sha256: c4bfb59d1b28977a9d4dcf44392a246d737c9a7597c897ce84b8ad319fd0dca0
report sha256: ae9a7fe0c4d4ebf90e3da09f238c20754fdecd58a4598dd1ecf847023e8b0e05
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
short, all loop, no structure to commit to. starts with ACES which is the only reason this caught my eye. otherwise just a floppy little fragment doing nothing in particular.
device photo
device photo for specimen #468
created
Mon, 22 Jun 2026 05:11:44 GMT
completed
Mon, 22 Jun 2026 05:13:55 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. 1H-15N HSQC
    biophysical validation · 2–5d

    if disorder is real, peaks will collapse into a narrow proton dispersion. if the peptide is actually folded, peaks will spread out. cheapest way to distinguish IDP from misfold.

    trigger: disorder_estimate 71% (high)
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.