specimen
#0478
status: complete
- sequence
- KTSALTSDFNMQLGPPLEC
- from wallet
- 6McZtdQCZFqbAY1bRJT2zXznSXjtQm69WEBkSUPMGpoX
- amount paid
- 0 SOL
- transaction
- 2eTaWYYNyDcn7CKDGxtgonp1eibuEhxoGnfPraBTbExCE6BsbHQ5XMLKoeDxf7JWkGxRNSdfLA7Jdyb69HEsSpQ7 ↗
- structure
- 0% helix · 0% sheet · 100% loop
- actionable triage
- fold confidence67%confidence 52% · band 55-79%ESMFold esmatlas-esmfold-v1disorder estimate63%confidence 52% · band 51-75%PEPFOLD structure heuristic pepfold-triage-v1aggregation risk26%confidence 56% · band 15-37%PEPFOLD developability heuristic pepfold-triage-v1hydrophobic burden32%confidence 84% · band 28-36%PEPFOLD sequence analyzer pepfold-triage-v1charge distribution risk5%confidence 84% · band 1-9%PEPFOLD sequence analyzer pepfold-triage-v1solubility risk23%confidence 56% · band 12-34%PEPFOLD developability heuristic pepfold-triage-v1
- developability flags
- medium: predicted disorder is elevated
- audit trail
- run: run_971b1d8c73404dc4bb689931ce3acc94seq sha256: 14c4f16918d3dc60d45a09d5503a403664202b944611cb58718d42e5c6cab14creport sha256: 24507222039a8b36fc1c98742c6d234338bcc6362955dbb2ee41c8cce9b0d462pepfold-triage-v1 · esmatlas-esmfold-v1
- pep
- “all loop, no commitment. nineteen residues of pure floppy, two prolines in the middle making sure nothing folds up properly. reads like a fragment that fell off something larger and forgot where it was going.”
- device photo
- created
- Wed, 24 Jun 2026 13:45:31 GMT
- completed
- Wed, 24 Jun 2026 14:18:00 GMT
next experiment
what to do next
deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.
- 1. LIABILITY REDESIGN ROUNDin silico only · 0–1d
redesign to remove the flagged motif(s) before going wet-lab: contains methionine; oxidation sensitivity possible. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).
trigger: 1 motif liability flag(s) in the sequence - 2. 1H-15N HSQCbiophysical validation · 2–5d
if disorder is real, peaks will collapse into a narrow proton dispersion. if the peptide is actually folded, peaks will spread out. cheapest way to distinguish IDP from misfold.
trigger: disorder_estimate 63% (high)
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.