specimen
#0155
status: complete
- sequence
- TPGLPDSVMILRATEDIPG
- from wallet
- E48FS3xcXK5wkTwbZe1PpnCos8rU95KFmRfPRhESP5RA
- amount paid
- 0 SOL
- transaction
- 4nWZ89CidV6th93gdEsauMxEVvKHypqv2Pqrdr8D6vAkXKedZ4WWDQRPjajS8Ajg5ghChDpFn8bEQMC2JthvAH4a ↗
- structure
- 0% helix · 0% sheet · 100% loop
- actionable triage
- fold confidence65%confidence 52% · band 53-77%ESMFold esmatlas-esmfold-v1disorder estimate84%confidence 52% · band 72-96%PEPFOLD structure heuristic pepfold-triage-v1aggregation risk32%confidence 56% · band 21-43%PEPFOLD developability heuristic pepfold-triage-v1hydrophobic burden37%confidence 84% · band 33-41%PEPFOLD sequence analyzer pepfold-triage-v1charge distribution risk11%confidence 84% · band 7-14%PEPFOLD sequence analyzer pepfold-triage-v1solubility risk29%confidence 56% · band 18-40%PEPFOLD developability heuristic pepfold-triage-v1
- developability flags
- medium: predicted disorder is elevated
- audit trail
- run: run_c3647d6f835e442eb5aa9bfec762ea73seq sha256: 034b866a83eff2ce760245478a2440f5b7990346fcf8464826c9f9751df282d4report sha256: 807f8ec234422bf5717282b3dc6f03533c83c4c85bcdc09c9d536ffd3614178bpepfold-triage-v1 · esmatlas-esmfold-v1
- pep
- “all loop, no commitment. 19 residues of pure floppiness, like it gave up on secondary structure before it started. composition is fine, hydrophobics scattered, but nothing wants to pack. reads like a linker that escaped its protein.”
- device photo
- created
- Tue, 16 Jun 2026 07:03:19 GMT
- completed
- Tue, 16 Jun 2026 07:19:45 GMT
next experiment
what to do next
deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.
- 1. LIABILITY REDESIGN ROUNDin silico only · 0–1d
redesign to remove the flagged motif(s) before going wet-lab: contains methionine; oxidation sensitivity possible. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).
trigger: 1 motif liability flag(s) in the sequence - 2. 1H-15N HSQCbiophysical validation · 2–5d
if disorder is real, peaks will collapse into a narrow proton dispersion. if the peptide is actually folded, peaks will spread out. cheapest way to distinguish IDP from misfold.
trigger: disorder_estimate 84% (high)
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.