pepscanPepScan
specimen

#0038

status: complete
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sequence
CNCKAPETALCARRCQQH
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence69%
confidence 52% · band 57-81%
ESMFold esmatlas-esmfold-v1
disorder estimate44%
confidence 52% · band 32-56%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk19%
confidence 56% · band 8-30%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden22%
confidence 84% · band 18-26%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk11%
confidence 84% · band 7-15%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk18%
confidence 56% · band 7-29%
PEPFOLD developability heuristic pepfold-triage-v1
audit trail
run: run_d1dfcab9e1f24555ae94daa268943bd3
seq sha256: 9d93678f552209eff327c420b2a8947b93bb75f004d823adfbd23127bcfe5f77
report sha256: bbda1773556ca34f9b50c0df2c58f5516b4d2f61fa6cb71bf80b9958d17b774d
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
“four cysteines in 18 residues. this thing is held together by disulfides or it isn't held together at all. spells CNCKAPETAL... almost wrote CAR PETAL in there. flowery for a cystine knot.”
device photo
device photo for specimen #38
created
Tue, 16 Jun 2026 04:05:06 GMT
completed
Tue, 16 Jun 2026 04:20:49 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. LIABILITY REDESIGN ROUND
    in silico only · 0–1d

    redesign to remove the flagged motif(s) before going wet-lab: multiple cysteines; disulfide heterogeneity risk. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).

    trigger: 1 motif liability flag(s) in the sequence
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.