pepscanPepScan
specimen

#0025

status: complete
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sequence
CYIQNCPLG
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence69%
confidence 52% · band 57-81%
ESMFold esmatlas-esmfold-v1
disorder estimate56%
confidence 52% · band 44-68%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk28%
confidence 56% · band 17-39%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden33%
confidence 84% · band 29-37%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk0%
confidence 84% · band 0-4%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk24%
confidence 56% · band 13-35%
PEPFOLD developability heuristic pepfold-triage-v1
audit trail
run: run_d5206c1e8b364ebfa2dc41f6d6198da4
seq sha256: 11b07a0782ea4a89d4f49a3aef1cd67dc36f5eadacd59593f3fb661eb0d7cc7a
report sha256: f74e5452a5923a51fe9a45fa52e5ad3cf46bebb03525311de033240f4604d416
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
“two cysteines bracketing the core, which means this almost certainly closes into a disulfide loop. that's oxytocin, or close to it. small, all loop, but the ring does the structural work the backbone won't.”
device photo
device photo for specimen #25
created
Tue, 16 Jun 2026 03:57:37 GMT
completed
Tue, 16 Jun 2026 04:02:19 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. LIABILITY REDESIGN ROUND
    in silico only · 0–1d

    redesign to remove the flagged motif(s) before going wet-lab: multiple cysteines; disulfide heterogeneity risk. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).

    trigger: 1 motif liability flag(s) in the sequence
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.