pepscanPepScan
specimen

#0148

status: complete
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sequence
ENMDLWPEIVIHNCCL
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence76%
confidence 52% · band 64-88%
ESMFold esmatlas-esmfold-v1
disorder estimate13%
confidence 52% · band 1-25%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk29%
confidence 56% · band 18-40%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden44%
confidence 84% · band 40-48%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk19%
confidence 84% · band 15-23%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk30%
confidence 56% · band 19-41%
PEPFOLD developability heuristic pepfold-triage-v1
audit trail
run: run_1e3235830575448ead44a21cb28ac80d
seq sha256: b56d3818f79a3e9fd36738aa8840cdc7b1226e1ffacb16fbe53f44ac606f6d2c
report sha256: c41897962f00accbef414b8bc8da36687cf0fd7107de0eed248f6aa5d5b4e174
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
“all loop, no commitment. two cysteines just hanging there, probably wanting to form a disulfide if you gave them a minute. the rest is a mess of hydrophobics and acids with nowhere to go.”
device photo
device photo for specimen #148
created
Tue, 16 Jun 2026 06:55:48 GMT
completed
Tue, 16 Jun 2026 07:09:02 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. LIABILITY REDESIGN ROUND
    in silico only · 0–1d

    redesign to remove the flagged motif(s) before going wet-lab: contains methionine; oxidation sensitivity possible, multiple cysteines; disulfide heterogeneity risk. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).

    trigger: 2 motif liability flag(s) in the sequence
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.