specimen
#0253
status: complete
- sequence
- VNTCEALDISLEQGPLAMSI
- from wallet
- FfahYUaxVPvrBMhSocHb4y4tqW3XHDSJ2puWoD2aLRqm
- amount paid
- 0 SOL
- transaction
- 3ECMqNCR1uPG8KVXSSo3U59Ympvqzxrod1LmLdAwokDV1yWSakmqJGYP2W6BWazLXEtmH2nLhRhXuMxBx1HXd4tB ↗
- structure
- 0% helix · 0% sheet · 100% loop
- actionable triage
- fold confidence64%confidence 52% · band 52-76%ESMFold esmatlas-esmfold-v1disorder estimate70%confidence 52% · band 58-82%PEPFOLD structure heuristic pepfold-triage-v1aggregation risk34%confidence 56% · band 23-45%PEPFOLD developability heuristic pepfold-triage-v1hydrophobic burden45%confidence 84% · band 41-49%PEPFOLD sequence analyzer pepfold-triage-v1charge distribution risk15%confidence 84% · band 11-19%PEPFOLD sequence analyzer pepfold-triage-v1solubility risk33%confidence 56% · band 22-44%PEPFOLD developability heuristic pepfold-triage-v1
- developability flags
- medium: predicted disorder is elevated
- audit trail
- run: run_d65eaa9246804f56b05a08bb35a831cfseq sha256: 4887723ed6d36800ce902baea5bf93e6ceeb74659607c8c03a998a51c51857c4report sha256: ee1163b2c1f6de101da309e90bfbe579b94650bc77bc587ef19c5f327e30fbcepepfold-triage-v1 · esmatlas-esmfold-v1
- pep
- “all loop, no commitment. 20 residues that refuse to pick a fold, just drifting through conformational space. mixed composition too, nothing dominant enough to pull it into shape. kind of a shrug in peptide form.”
- device photo
- created
- Tue, 16 Jun 2026 08:48:09 GMT
- completed
- Tue, 16 Jun 2026 14:08:59 GMT
next experiment
what to do next
deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.
- 1. LIABILITY REDESIGN ROUNDin silico only · 0–1d
redesign to remove the flagged motif(s) before going wet-lab: contains methionine; oxidation sensitivity possible. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).
trigger: 1 motif liability flag(s) in the sequence - 2. 1H-15N HSQCbiophysical validation · 2–5d
if disorder is real, peaks will collapse into a narrow proton dispersion. if the peptide is actually folded, peaks will spread out. cheapest way to distinguish IDP from misfold.
trigger: disorder_estimate 70% (high)
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.