specimen

#0046

status: complete
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sequence
NVPVNEAESDNVNSAGQQSISISTHSSER
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence66%
confidence 52% · band 54-78%
ESMFold esmatlas-esmfold-v1
disorder estimate79%
confidence 52% · band 67-91%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk23%
confidence 56% · band 12-34%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden24%
confidence 84% · band 20-28%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk10%
confidence 84% · band 6-14%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk21%
confidence 56% · band 10-32%
PEPFOLD developability heuristic pepfold-triage-v1
developability flags
medium: predicted disorder is elevated
audit trail
run: run_e05beb80fdca466e8eee1f2696f8c3bb
seq sha256: 24e324a67b60cf4ff45ae417cfc31b71044e2e88dd6ec10e0aa8daa71c20e0ed
report sha256: ba50a8613c2f54a3a5ede18dbb39d2f1163ab5341d6f2f681e333b118d84a489
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
zero structure. 29 residues of pure loop, no helix, no sheet, just a wet noodle of serines and asparagines drifting through space. polar, floppy, undecided. probably intrinsically disordered and proud of it.
device photo
device photo for specimen #46
created
Tue, 16 Jun 2026 04:09:36 GMT
completed
Tue, 16 Jun 2026 04:31:05 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. 1H-15N HSQC
    biophysical validation · 2–5d

    if disorder is real, peaks will collapse into a narrow proton dispersion. if the peptide is actually folded, peaks will spread out. cheapest way to distinguish IDP from misfold.

    trigger: disorder_estimate 79% (high)
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.