specimen
#0049
status: complete
- sequence
- ATHSNEAGHMIGIEGLDLYIMKSPKRGSANYLVPVEFQVED
- from wallet
- BWtgNasjEiCX27teVeqcAQEi8iKpt4BTfbFK3e8A5AHK
- amount paid
- 0 SOL
- transaction
- 2tdb57mwTLnoQ3h59LWuZzougjEBZgC3yQvKie6rYUWvDooNWoAJUmpevPCQdBCRXeABApR9x7zTNBwt4deugoev ↗
- structure
- 0% helix · 0% sheet · 100% loop
- actionable triage
- fold confidence48%confidence 52% · band 36-60%ESMFold esmatlas-esmfold-v1disorder estimate100%confidence 52% · band 88-100%PEPFOLD structure heuristic pepfold-triage-v1aggregation risk36%confidence 56% · band 25-47%PEPFOLD developability heuristic pepfold-triage-v1hydrophobic burden42%confidence 84% · band 38-46%PEPFOLD sequence analyzer pepfold-triage-v1charge distribution risk7%confidence 84% · band 3-11%PEPFOLD sequence analyzer pepfold-triage-v1solubility risk31%confidence 56% · band 20-42%PEPFOLD developability heuristic pepfold-triage-v1
- developability flags
- medium: structure confidence is limitedmedium: predicted disorder is elevated
- audit trail
- run: run_73cb48e3565d417aa02879473d3010dfseq sha256: ef3cda3e0da5788b510116c6209c93edc7316ea7f97e1e69eb24c3c93703c24areport sha256: 94d58fc1150e4ff862af6c8f49576545f3454d15fa5bb4c8892670a1771647abpepfold-triage-v1 · esmatlas-esmfold-v1
- pep
- “41 residues of pure loop. nothing folds, nothing commits, just one long noodle drifting through space. composition is mixed enough that it should do something, but it just... doesn't.”
- device photo
- created
- Tue, 16 Jun 2026 04:11:17 GMT
- completed
- Tue, 16 Jun 2026 04:35:27 GMT
next experiment
what to do next
deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.
- 1. LIABILITY REDESIGN ROUNDin silico only · 0–1d
redesign to remove the flagged motif(s) before going wet-lab: contains methionine; oxidation sensitivity possible. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).
trigger: 1 motif liability flag(s) in the sequence - 2. CD SPECTROSCOPYbiophysical validation · 1–3d
experimental secondary structure check. confirms whether the predicted helix/sheet content matches a real spectrum before committing to higher-cost assays.
trigger: fold_confidence 48% (model is uncertain) - 3. 1H-15N HSQCbiophysical validation · 2–5d
if disorder is real, peaks will collapse into a narrow proton dispersion. if the peptide is actually folded, peaks will spread out. cheapest way to distinguish IDP from misfold.
trigger: disorder_estimate 100% (high)
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.