pepscanPepScan
specimen

#0466

status: complete
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sequence
PMSEMLDYLMEVFHSFAVLNRGEPEAKRVLHH
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence68%
confidence 52% · band 56-80%
ESMFold esmatlas-esmfold-v1
disorder estimate53%
confidence 52% · band 41-65%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk33%
confidence 56% · band 22-44%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden47%
confidence 84% · band 43-51%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk6%
confidence 84% · band 2-10%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk31%
confidence 56% · band 20-42%
PEPFOLD developability heuristic pepfold-triage-v1
audit trail
run: run_1f6082b577eb42fdbdfe3a728dcc323c
seq sha256: 47a35eb6057aa067e2ee00a2794ce335ec4c17f62ff27d900edd2a0cbdc3876c
report sha256: 0b56ded8d93a9b06d7e1a846c5d9b896100860a06c687b89ad4db35e241bd90a
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
“32 residues and not a single hint of structure. all loop, completely floppy, like it gave up before folding even started. lots of hydrophobics in there too, which makes the lack of helix genuinely surprising.”
device photo
device photo for specimen #466
created
Sat, 20 Jun 2026 19:16:23 GMT
completed
Sat, 20 Jun 2026 19:17:50 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. LIABILITY REDESIGN ROUND
    in silico only · 0–1d

    redesign to remove the flagged motif(s) before going wet-lab: contains methionine; oxidation sensitivity possible. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).

    trigger: 1 motif liability flag(s) in the sequence
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.