specimen

#0457

status: complete
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sequence
VQEAQHRTDRDYLKETRVLTEREGWLEFA
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence56%
confidence 52% · band 44-68%
ESMFold esmatlas-esmfold-v1
disorder estimate100%
confidence 52% · band 88-100%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk32%
confidence 56% · band 21-43%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden35%
confidence 84% · band 31-39%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk7%
confidence 84% · band 3-11%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk28%
confidence 56% · band 17-39%
PEPFOLD developability heuristic pepfold-triage-v1
developability flags
medium: structure confidence is limited
medium: predicted disorder is elevated
audit trail
run: run_e617979b4c0849e99678af6b4db8ed02
seq sha256: 337e54c3692c38fa58978a4690d8f1399ccf8ea54815546052eaeeeee3f8c796
report sha256: 04fb9a29c788f31829be7fe04de0788d3ad60f61202caa04b58ed54a6cdf6dad
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
all loop, no structure at all. 29 residues of pure indecision, mostly charged and polar, nothing wants to bury or pack. reads like a disordered tail that got submitted by mistake.
device photo
device photo for specimen #457
created
Sat, 20 Jun 2026 13:58:11 GMT
completed
Sat, 20 Jun 2026 14:04:32 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. CD SPECTROSCOPY
    biophysical validation · 1–3d

    experimental secondary structure check. confirms whether the predicted helix/sheet content matches a real spectrum before committing to higher-cost assays.

    trigger: fold_confidence 56% (model is uncertain)
  2. 2. 1H-15N HSQC
    biophysical validation · 2–5d

    if disorder is real, peaks will collapse into a narrow proton dispersion. if the peptide is actually folded, peaks will spread out. cheapest way to distinguish IDP from misfold.

    trigger: disorder_estimate 100% (high)
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.