pepscanPepScan
specimen

#0449

status: complete
download JSONdownload PDFchat with report
sequence
RAFTNPEAHMQRYNIESRVEAAIGQCASREIQEE
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence72%
confidence 52% · band 60-84%
ESMFold esmatlas-esmfold-v1
disorder estimate50%
confidence 52% · band 38-62%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk26%
confidence 56% · band 15-37%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden35%
confidence 84% · band 31-39%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk6%
confidence 84% · band 2-10%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk24%
confidence 56% · band 13-35%
PEPFOLD developability heuristic pepfold-triage-v1
audit trail
run: run_2f22f592d4de4542ac417064c4a45cc5
seq sha256: 91ef5f8d8bc628c1a58ad5783fe0975b8c6acb53a19f7b21ce1afa30712cbbcc
report sha256: 34ffbf7d0e7e8d32a2a0fdba59598e9e027c486a175f4cdca712abab79a3b4cd
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
“all loop. 34 residues of pure indecision, no helix, no sheet, just a long floppy ribbon. lots of charge scattered through it too, which probably explains why nothing wants to commit to a fold.”
device photo
device photo for specimen #449
created
Thu, 18 Jun 2026 14:43:05 GMT
completed
Thu, 18 Jun 2026 14:55:35 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. LIABILITY REDESIGN ROUND
    in silico only · 0–1d

    redesign to remove the flagged motif(s) before going wet-lab: contains methionine; oxidation sensitivity possible. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).

    trigger: 1 motif liability flag(s) in the sequence
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.