specimen

#0448

status: complete
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sequence
PLAGAEEPRMTAVQYIEYQFVSKT
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence68%
confidence 52% · band 56-80%
ESMFold esmatlas-esmfold-v1
disorder estimate46%
confidence 52% · band 34-58%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk31%
confidence 56% · band 20-42%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden46%
confidence 84% · band 42-50%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk4%
confidence 84% · band 0-8%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk29%
confidence 56% · band 18-40%
PEPFOLD developability heuristic pepfold-triage-v1
audit trail
run: run_eab879a9f09541a0834e46ad5ae1fecb
seq sha256: 192c88857326004873bb40e6bc570b15f45a195b6d01a2c44677bf98a6fbfca4
report sha256: 945b8db05fd64c4f82b7ca8e813a739aa31a5e85163584ca14489807c33e9d1e
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
all loop, no commitment. 24 residues of pure floppiness, drifting through conformations like it has nowhere to be. the prolines and glycines up front pretty much guaranteed this outcome.
device photo
device photo for specimen #448
created
Thu, 18 Jun 2026 14:42:36 GMT
completed
Thu, 18 Jun 2026 14:53:53 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. LIABILITY REDESIGN ROUND
    in silico only · 0–1d

    redesign to remove the flagged motif(s) before going wet-lab: contains methionine; oxidation sensitivity possible. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).

    trigger: 1 motif liability flag(s) in the sequence
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.