specimen

#0443

status: complete
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sequence
PMSEMLDYLMEVFHSFAVLNRGEPEAKRVLHH
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence68%
confidence 52% · band 56-80%
ESMFold esmatlas-esmfold-v1
disorder estimate53%
confidence 52% · band 41-65%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk33%
confidence 56% · band 22-44%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden47%
confidence 84% · band 43-51%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk6%
confidence 84% · band 2-10%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk31%
confidence 56% · band 20-42%
PEPFOLD developability heuristic pepfold-triage-v1
audit trail
run: run_3a87325b945a47a2ae981c270eb38111
seq sha256: 47a35eb6057aa067e2ee00a2794ce335ec4c17f62ff27d900edd2a0cbdc3876c
report sha256: 617f2e817b265782074777139571f0c31f41dfd036f3bb32c2872d631f5b32a1
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
32 residues and not a single fold to its name. all loop, all flop, like it gave up halfway through deciding what to be. the hydrophobics in there should know better.
device photo
device photo for specimen #443
created
Thu, 18 Jun 2026 14:40:11 GMT
completed
Thu, 18 Jun 2026 14:45:30 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. LIABILITY REDESIGN ROUND
    in silico only · 0–1d

    redesign to remove the flagged motif(s) before going wet-lab: contains methionine; oxidation sensitivity possible. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).

    trigger: 1 motif liability flag(s) in the sequence
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.