#0436
- sequence
- PTCSDIFSSFGTPQPHTHAPNIATGNMGIHPILILVLHTPCPTAFNAQTGPALRINGESAGK
- from wallet
- 6F4J6AdT5iQx4ExeN7JFE7EEM6fJ1XJ3DRUHT56gMfWF
- amount paid
- 0 SOL
- transaction
- 2R81A9EeLvkeER76qPr9hbS7q4NK4tHH5iZvW69zJA7S3ZJFq3VmXrWd1kjk4qVyCiL4qrCyDKHeUMHdJXtT6Khc ↗
- structure
- 0% helix · 0% sheet · 100% loop
- actionable triage
- fold confidence42%confidence 52% · band 30-54%ESMFold esmatlas-esmfold-v1disorder estimate100%confidence 52% · band 88-100%PEPFOLD structure heuristic pepfold-triage-v1aggregation risk30%confidence 56% · band 19-41%PEPFOLD developability heuristic pepfold-triage-v1hydrophobic burden34%confidence 84% · band 30-38%PEPFOLD sequence analyzer pepfold-triage-v1charge distribution risk0%confidence 84% · band 0-4%PEPFOLD sequence analyzer pepfold-triage-v1solubility risk25%confidence 56% · band 14-36%PEPFOLD developability heuristic pepfold-triage-v1
- developability flags
- medium: structure confidence is limitedmedium: predicted disorder is elevated
- synthesis hints
- - sequence length >45 aa may reduce synthesis yield
- audit trail
- run: run_e2630ceb32fc47fbbe1cc10fa364ea57seq sha256: 55bb6354edf25a479a3235d0ab476f1a54bec2bb3b4c6bc42e312edd19bf1fd8report sha256: e58c208751b5adea95c1b31f0091d3be60af035cb005c86ea411d47aa75ba8a3pepfold-triage-v1 · esmatlas-esmfold-v1
- pep
- “62 residues of pure loop. no helix, no sheet, just a long noodle wandering through space. lots of prolines and threonines breaking everything up, which explains why nothing settles.”
- device photo
- created
- Thu, 18 Jun 2026 06:05:00 GMT
- completed
- Thu, 18 Jun 2026 06:19:26 GMT
what to do next
deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.
- 1. LIABILITY REDESIGN ROUNDin silico only · 0–1d
redesign to remove the flagged motif(s) before going wet-lab: potential deamidation motif (N-G), contains methionine; oxidation sensitivity possible, multiple cysteines; disulfide heterogeneity risk. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).
trigger: 4 motif liability flag(s) in the sequence - 2. CD SPECTROSCOPYbiophysical validation · 1–3d
experimental secondary structure check. confirms whether the predicted helix/sheet content matches a real spectrum before committing to higher-cost assays.
trigger: fold_confidence 42% (model is uncertain) - 3. 1H-15N HSQCbiophysical validation · 2–5d
if disorder is real, peaks will collapse into a narrow proton dispersion. if the peptide is actually folded, peaks will spread out. cheapest way to distinguish IDP from misfold.
trigger: disorder_estimate 100% (high)