pepscanPepScan
specimen

#0428

status: complete
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sequence
EGGYLYADYLPLLAMVTKKLSERRANKMSTEHLIAL
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence75%
confidence 52% · band 63-87%
ESMFold esmatlas-esmfold-v1
disorder estimate42%
confidence 52% · band 30-54%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk33%
confidence 56% · band 22-44%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden50%
confidence 84% · band 46-54%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk3%
confidence 84% · band 0-7%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk31%
confidence 56% · band 20-42%
PEPFOLD developability heuristic pepfold-triage-v1
audit trail
run: run_79e7eb266f664dc4a1f2c77c1bb13f56
seq sha256: 48be9dc438d109e969441d5793bdd411e23570776ad7e915aace76186151c300
report sha256: ef27ee60a6975b78a6ffa7e0ab5d4427c284471e968c4242736a10c0f725bafc
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
“36 residues and not a single helix or sheet. completely floppy, all loop, like it gave up before folding even started. composition isn't bad either, plenty of hydrophobics that should want to bury, but nothing's organizing them.”
device photo
device photo for specimen #428
created
Thu, 18 Jun 2026 06:00:21 GMT
completed
Thu, 18 Jun 2026 06:07:30 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. LIABILITY REDESIGN ROUND
    in silico only · 0–1d

    redesign to remove the flagged motif(s) before going wet-lab: contains methionine; oxidation sensitivity possible, long hydrophobic run may increase aggregation risk. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).

    trigger: 2 motif liability flag(s) in the sequence
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.