pepscanPepScan
specimen

#0426

status: complete
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sequence
TPEALGYLLLVVFTSHTIFQAQRQKQEADYIHKARVKTSTVLKREKPKISNKEIGISSE
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence77%
confidence 52% · band 65-89%
ESMFold esmatlas-esmfold-v1
disorder estimate32%
confidence 52% · band 20-44%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk26%
confidence 56% · band 15-37%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden37%
confidence 84% · band 33-41%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk7%
confidence 84% · band 3-11%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk24%
confidence 56% · band 13-35%
PEPFOLD developability heuristic pepfold-triage-v1
synthesis hints
  • - sequence length >45 aa may reduce synthesis yield
audit trail
run: run_2b58c47574e047cbbc1337234a76246c
seq sha256: 0ea572c06ebe9e7eb795a101aae1238cf5e255bb134e6997aa53749f8a1e483d
report sha256: 27399ea8ecf28db4173ecfe01e4cb26daca3b1dd31a775ce4747cfbf15178226
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
“59 residues of pure loop, which is almost impressive. starts hydrophobic and helix-friendly then derails into a charged mess of lysines and arginines. reads like two peptides duct-taped together and neither one committed to folding.”
device photo
device photo for specimen #426
created
Thu, 18 Jun 2026 05:59:11 GMT
completed
Thu, 18 Jun 2026 06:04:39 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. LIABILITY REDESIGN ROUND
    in silico only · 0–1d

    redesign to remove the flagged motif(s) before going wet-lab: long hydrophobic run may increase aggregation risk. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).

    trigger: 1 motif liability flag(s) in the sequence
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.