specimen

#0422

status: complete
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sequence
INSSVSVNVTLIASPEMPIYKRNR
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence71%
confidence 52% · band 59-83%
ESMFold esmatlas-esmfold-v1
disorder estimate46%
confidence 52% · band 34-58%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk29%
confidence 56% · band 18-40%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden42%
confidence 84% · band 38-46%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk8%
confidence 84% · band 4-12%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk28%
confidence 56% · band 17-39%
PEPFOLD developability heuristic pepfold-triage-v1
audit trail
run: run_47ddb4c9e4414355a3af544687f6a95e
seq sha256: 93530d8412cbd3a4b9573f3b8b0d7ee6bc84506a3fe95034dcc55fdd96ac8ed7
report sha256: e4e118671c301474bf2b4292650796193e195bf7e806ea23f71fec4e969b354d
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
all loop, no commitment. 24 residues of pure floppiness, no helix or sheet trying to form. the charged tail at the end is doing its own thing while the hydrophobic middle just sort of dangles.
device photo
device photo for specimen #422
created
Thu, 18 Jun 2026 05:56:50 GMT
completed
Thu, 18 Jun 2026 05:58:17 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. LIABILITY REDESIGN ROUND
    in silico only · 0–1d

    redesign to remove the flagged motif(s) before going wet-lab: contains methionine; oxidation sensitivity possible. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).

    trigger: 1 motif liability flag(s) in the sequence
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.