specimen
#0420
status: complete
- sequence
- AVEQAARCAQSNLLTDFGSQTLPFQAADMSEV
- from wallet
- CRJFU5HfNsiGofAQ152DJLLqg1FW5mhJj9arTrpE9zyi
- amount paid
- 0 SOL
- transaction
- 47wWtw7GdYG7KmLYA38z6p79Nj4GL2Qc1NrG5Kv12knazZ97tV57xKHbm3jtB2qwVpjDWC8JexmzTMum5o62Sp92 ↗
- structure
- 0% helix · 0% sheet · 100% loop
- actionable triage
- fold confidence58%confidence 52% · band 46-70%ESMFold esmatlas-esmfold-v1disorder estimate97%confidence 52% · band 85-100%PEPFOLD structure heuristic pepfold-triage-v1aggregation risk36%confidence 56% · band 25-47%PEPFOLD developability heuristic pepfold-triage-v1hydrophobic burden44%confidence 84% · band 40-48%PEPFOLD sequence analyzer pepfold-triage-v1charge distribution risk9%confidence 84% · band 5-13%PEPFOLD sequence analyzer pepfold-triage-v1solubility risk32%confidence 56% · band 21-43%PEPFOLD developability heuristic pepfold-triage-v1
- developability flags
- medium: structure confidence is limitedmedium: predicted disorder is elevated
- audit trail
- run: run_85f71f698e824b80b684fea3e9d37155seq sha256: 457539fd3e2329881ea2e5331a140d812039a4252b626e4f9d968ea07a6e7c53report sha256: 6e59f1bea50b85208794285192d6ded9fe2ffa4575352efd3e3dba77bef95bf0pepfold-triage-v1 · esmatlas-esmfold-v1
- pep
- “32 residues of pure loop. no helix, no sheet, just a long floppy ribbon doing whatever it wants. composition is mixed, nothing dominant, nothing committing. structurally it's a shrug.”
- device photo
- created
- Thu, 18 Jun 2026 04:27:31 GMT
- completed
- Thu, 18 Jun 2026 04:46:47 GMT
next experiment
what to do next
deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.
- 1. LIABILITY REDESIGN ROUNDin silico only · 0–1d
redesign to remove the flagged motif(s) before going wet-lab: contains methionine; oxidation sensitivity possible. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).
trigger: 1 motif liability flag(s) in the sequence - 2. CD SPECTROSCOPYbiophysical validation · 1–3d
experimental secondary structure check. confirms whether the predicted helix/sheet content matches a real spectrum before committing to higher-cost assays.
trigger: fold_confidence 58% (model is uncertain) - 3. 1H-15N HSQCbiophysical validation · 2–5d
if disorder is real, peaks will collapse into a narrow proton dispersion. if the peptide is actually folded, peaks will spread out. cheapest way to distinguish IDP from misfold.
trigger: disorder_estimate 97% (high)
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.