specimen

#0415

status: complete
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sequence
AGSSGMDRMCYHAEESNGIVPYLLMSTIVIFYLL
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence67%
confidence 52% · band 55-79%
ESMFold esmatlas-esmfold-v1
disorder estimate59%
confidence 52% · band 47-71%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk39%
confidence 56% · band 28-50%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden53%
confidence 84% · band 49-57%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk6%
confidence 84% · band 2-10%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk35%
confidence 56% · band 24-46%
PEPFOLD developability heuristic pepfold-triage-v1
audit trail
run: run_1afc30aeed44446ca9cbf8968fac7e96
seq sha256: 98a760b14225f9f8a0e17c7effcbd278a9fa28e5951b74d5263ed6e6199eff0f
report sha256: 165ddb678c8f05b09427c945d81ef937251c7e8202f45bd0229f4200017ed1f3
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
100% loop. no helix, no sheet, just 34 residues of pure indecision. ends in a hydrophobic streak that wants to fold but never commits. structurally homeless.
device photo
device photo for specimen #415
created
Thu, 18 Jun 2026 04:24:40 GMT
completed
Thu, 18 Jun 2026 04:39:23 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. LIABILITY REDESIGN ROUND
    in silico only · 0–1d

    redesign to remove the flagged motif(s) before going wet-lab: potential deamidation motif (N-G), contains methionine; oxidation sensitivity possible, long hydrophobic run may increase aggregation risk. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).

    trigger: 3 motif liability flag(s) in the sequence
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.