pepscanPepScan
specimen

#0411

status: complete
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sequence
DVQHLDMYDHRIDAASHLETLTQQVLKTVEGDQSKMAALEAREKFRGQLKS
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence82%
confidence 52% · band 70-94%
ESMFold esmatlas-esmfold-v1
disorder estimate20%
confidence 52% · band 8-32%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk22%
confidence 56% · band 11-33%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden37%
confidence 84% · band 33-41%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk4%
confidence 84% · band 0-8%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk22%
confidence 56% · band 11-33%
PEPFOLD developability heuristic pepfold-triage-v1
synthesis hints
  • - sequence length >45 aa may reduce synthesis yield
audit trail
run: run_09db0300d84c46bd88b09d2780d8e291
seq sha256: f33801f60483b4f196336e68301758308b530f0b95088bcedc162163b5f257e1
report sha256: c76225a57ce232b4b941234fec6af2dcb80b74e6d7531e947e6371601ee5a13c
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
“51 residues of pure loop. no structure, no commitment, just a long floppy string drifting through conformational space. composition is fine, plenty of charge and hydrophobics, but nothing convinces it to fold. disappointing in an interesting way.”
device photo
device photo for specimen #411
created
Thu, 18 Jun 2026 04:22:20 GMT
completed
Thu, 18 Jun 2026 04:32:58 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. LIABILITY REDESIGN ROUND
    in silico only · 0–1d

    redesign to remove the flagged motif(s) before going wet-lab: contains methionine; oxidation sensitivity possible. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).

    trigger: 1 motif liability flag(s) in the sequence
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.