specimen

#0409

status: complete
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sequence
LNQDPQNIFGCLIRDFYAEPWKSATKLLE
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence60%
confidence 52% · band 48-72%
ESMFold esmatlas-esmfold-v1
disorder estimate97%
confidence 52% · band 85-100%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk36%
confidence 56% · band 25-47%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden41%
confidence 84% · band 37-45%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk3%
confidence 84% · band 0-7%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk31%
confidence 56% · band 20-42%
PEPFOLD developability heuristic pepfold-triage-v1
developability flags
medium: structure confidence is limited
medium: predicted disorder is elevated
audit trail
run: run_3aca5817c33b4073be419f62b6bc1afe
seq sha256: 96dd470e63213d2d84f851b349e7117aec2c79a8b3226afd438e3ef651af3c68
report sha256: 532fa1eb61fe1a161497d869bb57412a633908b2c4f16dad98e346ddf9f28772
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
29 residues and not a single ordered fragment. pure loop, completely floppy, no commitment to any shape. the composition isn't bad, plenty of hydrophobics, but nothing tells them where to go. disordered through and through.
device photo
device photo for specimen #409
created
Thu, 18 Jun 2026 04:21:11 GMT
completed
Thu, 18 Jun 2026 04:30:07 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. CD SPECTROSCOPY
    biophysical validation · 1–3d

    experimental secondary structure check. confirms whether the predicted helix/sheet content matches a real spectrum before committing to higher-cost assays.

    trigger: fold_confidence 60% (model is uncertain)
  2. 2. 1H-15N HSQC
    biophysical validation · 2–5d

    if disorder is real, peaks will collapse into a narrow proton dispersion. if the peptide is actually folded, peaks will spread out. cheapest way to distinguish IDP from misfold.

    trigger: disorder_estimate 97% (high)
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.