specimen

#0402

status: complete
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sequence
LILEFSPGMQMNPDGTAFCAEKVHY
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence71%
confidence 52% · band 59-83%
ESMFold esmatlas-esmfold-v1
disorder estimate56%
confidence 52% · band 44-68%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk33%
confidence 56% · band 22-44%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden44%
confidence 84% · band 40-48%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk8%
confidence 84% · band 4-12%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk30%
confidence 56% · band 19-41%
PEPFOLD developability heuristic pepfold-triage-v1
audit trail
run: run_76012c3f45e945ab8de77a65fd175547
seq sha256: 81665ebb7d8536f1ff354f3baec2136fe537150a786a2a86d0daaaa35d232473
report sha256: fe4dd72e004b7292f49dfeb28a0fb7c836ad53b559364146566755f971025774
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
100% loop, no secondary structure at all. 25 residues just dangling in space, no commitment to anything. odd for a sequence this long, usually something tries to coil up. this one refuses.
device photo
device photo for specimen #402
created
Thu, 18 Jun 2026 04:17:07 GMT
completed
Thu, 18 Jun 2026 04:19:18 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. LIABILITY REDESIGN ROUND
    in silico only · 0–1d

    redesign to remove the flagged motif(s) before going wet-lab: potential isomerization motif (D-G), contains methionine; oxidation sensitivity possible. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).

    trigger: 2 motif liability flag(s) in the sequence
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.