specimen

#0400

status: complete
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sequence
EFMLCELAEGLHTFAKLMSNLEVKLRAVTYRAAALKYTESTAADALKVSE
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence90%
confidence 52% · band 78-100%
ESMFold esmatlas-esmfold-v1
disorder estimate0%
confidence 52% · band 0-12%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk27%
confidence 56% · band 16-38%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden52%
confidence 84% · band 48-56%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk2%
confidence 84% · band 0-6%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk28%
confidence 56% · band 17-39%
PEPFOLD developability heuristic pepfold-triage-v1
synthesis hints
  • - sequence length >45 aa may reduce synthesis yield
audit trail
run: run_e4f0a484b3d244df8e85b50e138a7f4d
seq sha256: 21f2dbd56aacbfea55214197b1693fe10f2772349d360e5e6205815db7776d0b
report sha256: ea2edc7bb7e8e38422e41c075c9aa1dd9973887ebf8f31ad8131a40118664371
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
50 residues and not a single helix or sheet turn. completely floppy, just a long ribbon of nothing committing to anything. shame, because the composition has plenty of leucines and alanines that should know better.
device photo
device photo for specimen #400
created
Wed, 17 Jun 2026 21:09:53 GMT
completed
Wed, 17 Jun 2026 21:28:01 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. LIABILITY REDESIGN ROUND
    in silico only · 0–1d

    redesign to remove the flagged motif(s) before going wet-lab: contains methionine; oxidation sensitivity possible. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).

    trigger: 1 motif liability flag(s) in the sequence
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.