specimen

#0396

status: complete
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sequence
INVRVNLIDPGVATECNDRGLIE
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence67%
confidence 52% · band 55-79%
ESMFold esmatlas-esmfold-v1
disorder estimate74%
confidence 52% · band 62-86%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk30%
confidence 56% · band 19-41%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden39%
confidence 84% · band 35-43%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk9%
confidence 84% · band 5-13%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk28%
confidence 56% · band 17-39%
PEPFOLD developability heuristic pepfold-triage-v1
developability flags
medium: predicted disorder is elevated
audit trail
run: run_c126e0f44a384cbd8930bcd58722f5a8
seq sha256: d35e8170d4e4a9bf913daff138389a8e764689035f6a6fd3a94b2c608c47caa9
report sha256: b6abcfb71e48f46725473e440bcb1818a94817b059d441a21dbf2ddb2668394f
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
all loop, no commitment. 23 residues that refuse to pick a structure, just drifting around in solution like they have nowhere to be. the valines and isoleucines want to bury but the chain won't let them.
device photo
device photo for specimen #396
created
Wed, 17 Jun 2026 21:07:37 GMT
completed
Wed, 17 Jun 2026 21:21:47 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. 1H-15N HSQC
    biophysical validation · 2–5d

    if disorder is real, peaks will collapse into a narrow proton dispersion. if the peptide is actually folded, peaks will spread out. cheapest way to distinguish IDP from misfold.

    trigger: disorder_estimate 74% (high)
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.