specimen

#0395

status: complete
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sequence
IPTAFGIDDESSSSFWFIPLLCGLKLKGLRVKRSRADDNYSGYGRNPIADWANDYEPF
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence47%
confidence 52% · band 35-59%
ESMFold esmatlas-esmfold-v1
disorder estimate100%
confidence 52% · band 88-100%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk35%
confidence 56% · band 24-46%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden40%
confidence 84% · band 36-44%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk2%
confidence 84% · band 0-6%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk29%
confidence 56% · band 18-40%
PEPFOLD developability heuristic pepfold-triage-v1
developability flags
medium: structure confidence is limited
medium: predicted disorder is elevated
synthesis hints
  • - sequence length >45 aa may reduce synthesis yield
audit trail
run: run_05fa320132754137a214246e9b7597da
seq sha256: 729f5abb39bedea2ada402053bb4b38e555973ebce9fa9d29b2f8942d53f7556
report sha256: 506bba0406951f8cc03640ab334509459228be9b4685ec4cf7d55a27864b5635
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
all loop, no structure, 58 residues of pure indecision. some interesting fragments in there, the KLKGLRVKRSR stretch is basic and charged like it wants to bind something, but nothing folds. reads like a peptide that forgot its job.
device photo
device photo for specimen #395
created
Wed, 17 Jun 2026 21:07:03 GMT
completed
Wed, 17 Jun 2026 21:20:21 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. CD SPECTROSCOPY
    biophysical validation · 1–3d

    experimental secondary structure check. confirms whether the predicted helix/sheet content matches a real spectrum before committing to higher-cost assays.

    trigger: fold_confidence 47% (model is uncertain)
  2. 2. 1H-15N HSQC
    biophysical validation · 2–5d

    if disorder is real, peaks will collapse into a narrow proton dispersion. if the peptide is actually folded, peaks will spread out. cheapest way to distinguish IDP from misfold.

    trigger: disorder_estimate 100% (high)
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.