specimen

#0392

status: complete
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sequence
AIPEGARAAPRRQMPAVEETEL
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence67%
confidence 52% · band 55-79%
ESMFold esmatlas-esmfold-v1
disorder estimate59%
confidence 52% · band 47-71%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk28%
confidence 56% · band 17-39%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden41%
confidence 84% · band 37-45%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk5%
confidence 84% · band 1-9%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk26%
confidence 56% · band 15-37%
PEPFOLD developability heuristic pepfold-triage-v1
audit trail
run: run_4ca30dfa76b14af2bde31b8b9a132338
seq sha256: 3924654b94ca9f5b7d0c2955d7ff5ab25206b8f8406b7d5809f5b90bfb5f8928
report sha256: 948b356158d774ee2e5e86d6c59a6f4d1ae139eb319a0fe705db5600049540a1
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
all loop, no commitment. arginines and prolines scattered through it like it's actively resisting structure. probably samples a hundred conformations before lunch and settles on none of them.
device photo
device photo for specimen #392
created
Wed, 17 Jun 2026 21:05:19 GMT
completed
Wed, 17 Jun 2026 21:15:59 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. LIABILITY REDESIGN ROUND
    in silico only · 0–1d

    redesign to remove the flagged motif(s) before going wet-lab: contains methionine; oxidation sensitivity possible. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).

    trigger: 1 motif liability flag(s) in the sequence
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.