pepscanPepScan
specimen

#0391

status: complete
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sequence
KQRLHMLSAVLFAFRIFITKGDSEYI
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence75%
confidence 52% · band 63-87%
ESMFold esmatlas-esmfold-v1
disorder estimate27%
confidence 52% · band 15-39%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk37%
confidence 56% · band 26-48%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden54%
confidence 84% · band 50-58%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk8%
confidence 84% · band 4-12%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk35%
confidence 56% · band 24-46%
PEPFOLD developability heuristic pepfold-triage-v1
audit trail
run: run_65268bd86fb6424f871772314e225c26
seq sha256: d38e198c592ef2c87b0ea093c3ac20c72ad9bad4b852faddd737017f3c576888
report sha256: 798aebc808be823d01a3c67f4373c46558262a30dd5c059660c5331aa3ceff29
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
“all loop, zero secondary structure. 26 residues of pure indecision, despite a hydrophobic stretch in the middle that should want to bury itself. reads like a transmembrane fragment that forgot its membrane.”
device photo
device photo for specimen #391
created
Wed, 17 Jun 2026 21:04:45 GMT
completed
Wed, 17 Jun 2026 21:14:34 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. LIABILITY REDESIGN ROUND
    in silico only · 0–1d

    redesign to remove the flagged motif(s) before going wet-lab: contains methionine; oxidation sensitivity possible, long hydrophobic run may increase aggregation risk. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).

    trigger: 2 motif liability flag(s) in the sequence
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.