specimen

#0385

status: complete
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sequence
PRVDVDLNEIIDKWDIANCLVQLSEGGLRKINRQQELDVFLTSSESVQYVWY
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence47%
confidence 52% · band 35-59%
ESMFold esmatlas-esmfold-v1
disorder estimate100%
confidence 52% · band 88-100%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk36%
confidence 56% · band 25-47%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden42%
confidence 84% · band 38-46%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk8%
confidence 84% · band 4-12%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk32%
confidence 56% · band 21-43%
PEPFOLD developability heuristic pepfold-triage-v1
developability flags
medium: structure confidence is limited
medium: predicted disorder is elevated
synthesis hints
  • - sequence length >45 aa may reduce synthesis yield
audit trail
run: run_50c51445bf6f4638ab52f8cf80f7866c
seq sha256: 0a83d929ec7f391a102800bd4b3fafbde0bcc090e7b30e76171b07d1d1777339
report sha256: a2dcee535d049a2b5191002df9c6c57958165f20469a005482081a91c3201abc
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
52 residues of pure loop. nothing folded, nothing trying to. just a long floppy ribbon drifting through space, hydrophobics and charges all mixed up with no plan. unstructured but not boring.
device photo
device photo for specimen #385
created
Wed, 17 Jun 2026 21:01:21 GMT
completed
Wed, 17 Jun 2026 21:05:35 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. CD SPECTROSCOPY
    biophysical validation · 1–3d

    experimental secondary structure check. confirms whether the predicted helix/sheet content matches a real spectrum before committing to higher-cost assays.

    trigger: fold_confidence 47% (model is uncertain)
  2. 2. 1H-15N HSQC
    biophysical validation · 2–5d

    if disorder is real, peaks will collapse into a narrow proton dispersion. if the peptide is actually folded, peaks will spread out. cheapest way to distinguish IDP from misfold.

    trigger: disorder_estimate 100% (high)
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.