#0384
- sequence
- DGLMYDWAAHGAFNLSASLNGRRRSWVADGFFEGGLKVNDIEEMRLHSLLLVMLQNN
- from wallet
- 62ef4jLfuT2zYFwBsTqHCHXMWkHAPiNn7dfeEn8qj37Q
- amount paid
- 0 SOL
- transaction
- 2kFkfuroHYCpebwjSCUNeQKgjQBkUi452J44USZyADXi5DTE7mCYxdq2WruEu6JZui3KYxVw1155KQiSZdSPuMh5 ↗
- structure
- 0% helix · 0% sheet · 100% loop
- actionable triage
- fold confidence50%confidence 52% · band 38-62%ESMFold esmatlas-esmfold-v1disorder estimate100%confidence 52% · band 88-100%PEPFOLD structure heuristic pepfold-triage-v1aggregation risk39%confidence 56% · band 28-50%PEPFOLD developability heuristic pepfold-triage-v1hydrophobic burden47%confidence 84% · band 43-51%PEPFOLD sequence analyzer pepfold-triage-v1charge distribution risk4%confidence 84% · band 0-8%PEPFOLD sequence analyzer pepfold-triage-v1solubility risk33%confidence 56% · band 22-44%PEPFOLD developability heuristic pepfold-triage-v1
- developability flags
- medium: structure confidence is limitedmedium: predicted disorder is elevated
- synthesis hints
- - sequence length >45 aa may reduce synthesis yield
- audit trail
- run: run_fb8ded3454554813abda4b016c0374c2seq sha256: f23bc6e48aef14cb4021c279c6947c52d36276116997ffc2cdbf81c65071e407report sha256: e57e8c8765008813f5cceec71965f7826e6947c8aaadd8c0f20fc9c47e32b997pepfold-triage-v1 · esmatlas-esmfold-v1
- pep
- “57 residues of pure loop. nothing committed to, nothing held. three arginines in a row try to start something and then the whole chain just gives up and keeps wandering.”
- device photo
- created
- Wed, 17 Jun 2026 21:00:47 GMT
- completed
- Wed, 17 Jun 2026 21:03:53 GMT
what to do next
deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.
- 1. LIABILITY REDESIGN ROUNDin silico only · 0–1d
redesign to remove the flagged motif(s) before going wet-lab: potential deamidation motif (N-G), potential isomerization motif (D-G), contains methionine; oxidation sensitivity possible. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).
trigger: 4 motif liability flag(s) in the sequence - 2. CD SPECTROSCOPYbiophysical validation · 1–3d
experimental secondary structure check. confirms whether the predicted helix/sheet content matches a real spectrum before committing to higher-cost assays.
trigger: fold_confidence 50% (model is uncertain) - 3. 1H-15N HSQCbiophysical validation · 2–5d
if disorder is real, peaks will collapse into a narrow proton dispersion. if the peptide is actually folded, peaks will spread out. cheapest way to distinguish IDP from misfold.
trigger: disorder_estimate 100% (high)